Skin is known to be able to regulate various physiological functions of the body. The skin can sense detailed information about all processes occurring in the internal organs and receive external information and react to irritation through mechanical action (e. g. acupuncture, massage), exposure to heat, electric current, magnetic field, biological field, laser or ultrasound. Skin can receive such information in the form of electric, optic, thermal, chemical, magnetic, mechanical and other signals, then process them and send them in encoded form to the regulating systems of the body. Skin is interconnected with internal organs and systems of the body. Therefore, any malfunctions occurring in the organs or systems of the body also influence the skin condition. So the skin carries information about the condition of the sick organs or malfunctions of the body systems. We can influence the sick organs and malfunctions in the body from the outside through the skin, while acting upon the certain skin areas. The electrical conduction, capacity, temperature and sensitivity of the skin change when something is going wrong in the body. Depending on the areas being irritated, body reactions upon the irritation are different as our nervous system adjusts the body functioning to the present environment the body lives in. The skin areas manifesting increased physiological activity are used for action during treatment of diseases with SCENAR-therapy. SCENAR and Cosmodic devices act upon the body with short-pulse low-frequency signals when the electrodes contact skin. Parameters of the acting signal are set automatically according to the biological feedbacks. In other words, when the electrodes touch the skin, the device receives information about the body’s state. Depending on the condition of the body the device forms and sends neuro-like impulses to the body. These impulses carry information necessary for normal functioning of the body organ or system. First of all, SCENAR and Cosmodic action is focused on normalization of the disordered functions of the body. The main objective here is providing harmony and stimulating the defensive forces and latent reserves of the body. In fact, it is not the device that treats your diseases, but your own body. It only helps the body to remember how the healthy organs should work and recover. The brain controls all organs and tissues by means of electric pulses. It follows, that we can act upon the body, internals and nervous system through skin using electric pulses, similar to the natural ones. SCENAR is the very device able to generate such electric pulses that are physiologically close to those imported to the brain.